Tissue architecture
Amnion and chorion are distinct layers. AmnioWrap2 retains both and the intermediate layer between them.
UNDERSTANDING TISSUE ALLOGRAFTS
Human tissue.
Native complexity.
A closer look at placental membranes, their structural role, and the practical questions that shape product selection and access.
Conceptual illustration
THE TISSUE FOUNDATION
What is a
tissue allograft?
An allograft is tissue donated by one person for use in another. Placental membrane allografts use tissues associated with the placenta, including amnion and chorion.
Products differ in tissue layers, processing, storage, and intended use. Understanding those differences is central to choosing and handling a product.
Extracellular matrix
The matrix forms a structural network within tissue. Product processing can affect which native components are retained.
A defined intended use
AmnioWrap2 is intended for homologous use as a protective covering. Follow its current instructions for use.
INSIDE THE ALLOGRAFT
The structure
is part of the story.
Placental membranes contain an extracellular matrix: a structural network that includes collagen and other tissue components. AmnioWrap2 retains the intermediate layer between the amnion and chorion.
Understand tissue allografts
H&E stain: nuclei appear purple; extracellular matrix appears pink. Original R812 product imagery.
COVERAGE & ACCESS
From product selection
to benefit verification.
A practical starting point for your clinic’s billing and authorization team.
Check the local policy.
Some tissue-based wound products may qualify for Medicare coverage when the applicable coverage and medical-necessity requirements are satisfied. The relevant Medicare Administrative Contractor policy and billing article must be checked for the patient’s jurisdiction.
CMS policy example · L36690Verify the exact product.
Commercial insurers set their own product-specific and indication-specific criteria. A plan may cover certain products while considering others investigational or unproven. Check the member’s actual benefits and current policy.
View a commercial payer policyCoverage is not guaranteed for AmnioWrap2 or any individual claim. A product listing or code alone does not establish coverage. This information concerns tissue allografts, not PBME Topical. Reviewed October 2026; verify policies for the date of service.
EXPLORE THE PORTFOLIO
Meet AmnioWrap2.
Product details, original histology, handling information, and a dimensional sizing guide.